Manchester United Injury Update: Latest Return Dates for Sesko, Maguire, Mainoo and Martinez

Manchester United return to Premier League action this weekend, but the mood around Old Trafford is shaped heavily by the Manchester United injury update that continues to dominate the club’s preparations.

As Ruben Amorim prepares his squad for the visit of Everton, several senior players remain doubtful, while others edge closer to long-awaited returns. This Manchester United injury update arrives at a crucial moment, with United unbeaten in five league matches yet still searching for consistency.

The team’s recent run — including back-to-back 2-2 draws with Nottingham Forest and Tottenham — has offered both encouragement and frustration. Amorim’s early work is beginning to take shape, but the impact of fitness issues has left him with a challenging balancing act. With former manager David Moyes returning to Old Trafford in charge of Everton, the timing of this Manchester United injury update becomes even more significant.

Sesko ruled out: A major blow in the Manchester United injury update

The first major headline in the latest Manchester United injury update concerns star striker Benjamin Sesko, who has been ruled out for several weeks. The Slovenian forward suffered a knee problem late in the draw against Tottenham, forcing United to finish the match with ten men.

Sesko missed international duty due to the injury, and Amorim confirmed the setback when speaking to the media:

“He is going to be a few weeks out. Not that serious but we have to be careful. He is feeling better.”

This timeline means Sesko will miss the Everton match and likely several fixtures within the coming month. His absence reduces Amorim’s attacking options at a time when United had finally begun to develop a sharper cutting edge. This Manchester United injury update also indicates that Sesko could return around the festive period if recovery goes smoothly.

Harry Maguire setback included in Manchester United injury update

Another key concern highlighted in the Manchester United injury update is the fitness of Harry Maguire. The defender, who had recently fought his way back into the starting XI, suffered a hamstring injury against Spurs. Despite hope that the international break would support his recovery, Amorim confirmed: “Maguire is not ready.”

Maguire’s absence leaves United light at centre-back, especially as Lisandro Martínez is only just nearing full readiness. The defender’s leadership and aerial strength will be missed against an Everton side known for their physical style. According to the Manchester United injury update, Maguire is expected to return in December.

Kobbie Mainoo expected to feature despite concerns

Perhaps the most positive element in the latest Manchester United injury update centres on Kobbie Mainoo. The young midfielder missed the Tottenham match due to a minor knock and also sat out training on Friday. However, Amorim suggested the issue was not serious:

“Kobbie didn’t train today but we could see him tomorrow.”

This suggests Mainoo is likely to be available for the clash with Everton, offering United crucial control and energy in midfield. His presence is vital, and this Manchester United injury update indicates confidence that he will return just in time.

Lisandro Martínez nearing return in promising Manchester United injury update

Perhaps the most anticipated news in this Manchester United injury update concerns Lisandro Martínez. The defender has been sidelined since February with an ACL injury, but his steady rehabilitation is approaching its conclusion.

Martínez returned to full training before the international break and even joined up with Argentina to work with their medical and coaching staff—though he did not play. Amorim confirmed that the defender is close to returning: “Licha is getting close to be playing.”

With United having lacked stability in defence for much of the year, his reintroduction could transform Amorim’s back line. This Manchester United injury update suggests that Martínez has a strong chance of being included in the matchday squad against Everton.

Manchester United injury update: What it means for Everton clash

This weekend’s match is important not only for momentum but also for assessing how United cope under pressure with a depleted squad. The Manchester United injury update paints a picture of a team trying to build rhythm amid constant disruptions. With Sesko and Maguire unavailable, United must rely on depth and adaptability.

Everton, too, arrive fighting for points, making this a test of composure as much as quality. But the positive signs — especially the potential returns of Mainoo and Martínez — offer encouragement that United may soon move past the worst of their injury problems.